In vitro maturation (IVM) is the technique of letting the contents of ovarian follicles and the oocytes inside mature in vitro. It can be offered to woman with infertility problems, combined with IVF, offering women pregnancy without ovarian stimulation.
1) IVM involves a shorter treatment regimen compared to IVF, meaning a cycle of IVM takes less time than IVF.
2) IVM is less expensive.
3) IVM requires less fertility medication
IVM is still relatively new, and the overall success rates and long-term outcomes of IVM are unclear. Because the eggs collected via IVM are extremely sensitive, they need to be handled very carefully in the lab or risk losing them. Also, the outer part of these eggs can become tough for sperm to penetrate making ICSI required.